| Team: | North Carolina A&T | Rating: | -5.3793 | Average Socre: | 67.7188 |
| Conference: | Big South | ||||
| Wins: | 12 | Losses: | 20 | Div 1 Games: | 29 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 149 | UNC Greensboro (17 - 14) | 53 | 57 | |
| 11/13/2021 | L | at | 137 | Jacksonville (21 - 10) | 54 | 63 | |
| 11/15/2021 | L | at | 295 | South Florida (8 - 23) | 54 | 56 | |
| 11/18/2021 | W | Greensboro ( - ) | 77 | 69 | |||
| 11/20/2021 | L | at | 66 | Wake Forest (23 - 9) | 63 | 87 | |
| 11/23/2021 | L | at | 147 | Stanford (16 - 16) | 65 | 79 | |
| 11/26/2021 | L | 105 | Samford (21 - 11) | 75 | 77 | Niceville, FL | |
| 11/27/2021 | W | 326 | St. Francis NY (10 - 20) | 73 | 67 | Niceville, FL | |
| 12/03/2021 | W | Carver ( - ) | 97 | 55 | |||
| 12/07/2021 | L | at | 186 | East Carolina (15 - 15) | 71 | 82 | |
| 12/11/2021 | L | at | 117 | UCF (18 - 12) | 68 | 83 | |
| 12/14/2021 | W | at | 184 | East Tennessee St. (15 - 17) | 69 | 67 | |
| 12/18/2021 | L | at | 225 | Howard (16 - 13) | 57 | 79 | Newark, NJ |
| 12/21/2021 | W | Mid Atlantic Christian ( - ) | 88 | 63 | |||
| 01/05/2022 | W | 290 | Presbyterian (12 - 20) | 65 | 57 | ||
| 01/08/2022 | W | at | 287 | Radford (11 - 18) | 73 | 72 | |
| 01/12/2022 | W | 306 | Hampton (9 - 19) | 67 | 59 | ||
| 01/15/2022 | L | at | 239 | High Point (14 - 18) | 71 | 78 | |
| 01/19/2022 | W | at | 208 | UNC Asheville (16 - 14) | 73 | 71 | |
| 01/22/2022 | L | 198 | Campbell (16 - 13) | 72 | 73 | ||
| 01/26/2022 | L | at | 56 | Longwood (26 - 6) | 71 | 79 | |
| 01/29/2022 | L | 218 | USC Upstate (14 - 16) | 64 | 84 | ||
| 02/03/2022 | L | at | 84 | Winthrop (23 - 9) | 54 | 64 | |
| 02/05/2022 | L | at | 170 | Gardner Webb (18 - 13) | 62 | 69 | |
| 02/09/2022 | W | 353 | Charleston Southern (6 - 25) | 62 | 51 | ||
| 02/12/2022 | W | 56 | Longwood (26 - 6) | 70 | 62 | ||
| 02/16/2022 | L | at | 306 | Hampton (9 - 19) | 82 | 93 | |
| 02/19/2022 | L | at | 198 | Campbell (16 - 13) | 63 | 64 | |
| 02/23/2022 | L | 239 | High Point (14 - 18) | 58 | 78 | ||
| 02/26/2022 | L | 287 | Radford (11 - 18) | 53 | 62 | ||
| 03/02/2022 | W | at | 287 | Radford (11 - 18) | 78 | 71 | Charlotte, NC |
| 03/04/2022 | L | at | 56 | Longwood (26 - 6) | 65 | 79 | Charlotte, NC |