| Team: | Radford | Rating: | -5.3333 | Average Socre: | 63.1724 |
| Conference: | Big South | ||||
| Wins: | 11 | Losses: | 18 | Div 1 Games: | 27 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | Emory & Henry ( - ) | 84 | 72 | |||
| 11/12/2021 | L | at | 100 | Virginia (19 - 13) | 52 | 73 | |
| 11/15/2021 | L | at | 68 | Virginia Tech (23 - 12) | 39 | 65 | |
| 11/19/2021 | L | at | 77 | Furman (22 - 12) | 64 | 81 | |
| 11/20/2021 | L | 121 | Navy (21 - 11) | 33 | 47 | Greenville, SC | |
| 11/24/2021 | W | 346 | William & Mary (5 - 27) | 67 | 54 | ||
| 11/28/2021 | W | 298 | Eastern Kentucky (13 - 18) | 88 | 75 | ||
| 11/30/2021 | W | Kentucky Christian ( - ) | 79 | 70 | |||
| 12/04/2021 | L | at | 130 | West Virginia (16 - 17) | 51 | 67 | |
| 12/11/2021 | L | at | 182 | James Madison (15 - 14) | 70 | 79 | |
| 12/13/2021 | L | at | 236 | George Washington (12 - 18) | 58 | 67 | |
| 12/18/2021 | L | at | 28 | Davidson (27 - 6) | 54 | 74 | |
| 01/06/2022 | W | at | 218 | USC Upstate (14 - 16) | 82 | 77 | |
| 01/08/2022 | L | 289 | North Carolina A&T (12 - 20) | 72 | 73 | ||
| 01/12/2022 | L | 56 | Longwood (26 - 6) | 75 | 83 | ||
| 01/15/2022 | L | at | 198 | Campbell (16 - 13) | 58 | 70 | |
| 01/19/2022 | W | 306 | Hampton (9 - 19) | 54 | 51 | ||
| 01/22/2022 | L | 208 | UNC Asheville (16 - 14) | 74 | 78 | ||
| 01/26/2022 | L | at | 239 | High Point (14 - 18) | 58 | 63 | |
| 01/29/2022 | L | at | 170 | Gardner Webb (18 - 13) | 42 | 61 | |
| 02/02/2022 | W | 353 | Charleston Southern (6 - 25) | 64 | 52 | ||
| 02/05/2022 | L | 290 | Presbyterian (12 - 20) | 70 | 78 | ||
| 02/09/2022 | L | at | 84 | Winthrop (23 - 9) | 48 | 58 | |
| 02/12/2022 | W | at | 306 | Hampton (9 - 19) | 60 | 54 | |
| 02/16/2022 | W | 198 | Campbell (16 - 13) | 71 | 67 | ||
| 02/19/2022 | W | 239 | High Point (14 - 18) | 66 | 64 | ||
| 02/23/2022 | L | at | 56 | Longwood (26 - 6) | 66 | 71 | |
| 02/26/2022 | W | at | 289 | North Carolina A&T (12 - 20) | 62 | 53 | |
| 03/02/2022 | L | 289 | North Carolina A&T (12 - 20) | 71 | 78 | Charlotte, NC |