| Team: | Alabama St. | Rating: | -7.8 | Average Socre: | 69.6774 |
| Conference: | Southwestern | ||||
| Wins: | 10 | Losses: | 21 | Div 1 Games: | 30 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 144 | Western Kentucky (19 - 13) | 74 | 79 | |
| 11/10/2021 | L | at | 134 | Vanderbilt (17 - 16) | 72 | 91 | |
| 11/13/2021 | L | at | 57 | Missouri St. (23 - 10) | 60 | 78 | |
| 11/16/2021 | L | at | 81 | Iowa St. (20 - 12) | 60 | 68 | |
| 11/18/2021 | L | at | 30 | Iowa (26 - 9) | 82 | 108 | |
| 11/20/2021 | W | 241 | North Carolina Central (16 - 15) | 80 | 74 | ||
| 11/22/2021 | W | Tuskegee ( - ) | 91 | 65 | |||
| 11/28/2021 | L | 338 | North Alabama (9 - 21) | 69 | 81 | ||
| 12/01/2021 | L | at | 52 | Dayton (23 - 10) | 54 | 93 | |
| 12/08/2021 | L | 105 | Samford (21 - 11) | 64 | 74 | ||
| 12/11/2021 | L | at | 325 | Pepperdine (7 - 25) | 62 | 79 | |
| 12/22/2021 | L | at | 55 | Texas (21 - 11) | 48 | 68 | |
| 12/28/2021 | L | at | 31 | Texas Tech (25 - 9) | 53 | 75 | |
| 01/03/2022 | W | at | 356 | Mississippi Valley St. (2 - 26) | 84 | 75 | |
| 01/05/2022 | L | at | 347 | Arkansas Pine Bluff (7 - 24) | 68 | 70 | |
| 01/08/2022 | W | 299 | Jackson St. (11 - 19) | 72 | 57 | ||
| 01/10/2022 | L | 213 | Alcorn St. (17 - 16) | 60 | 70 | ||
| 01/15/2022 | W | 292 | Alabama A&M (12 - 18) | 59 | 55 | ||
| 01/22/2022 | L | at | 305 | Prairie View A&M (8 - 19) | 67 | 70 | |
| 01/24/2022 | L | at | 187 | Texas Southern (18 - 12) | 66 | 73 | |
| 01/29/2022 | W | 337 | Bethune Cookman (9 - 21) | 79 | 73 | Mobile, AL | |
| 01/31/2022 | L | 278 | Florida A&M (13 - 17) | 65 | 66 | ||
| 02/05/2022 | W | at | 294 | Grambling St. (12 - 20) | 80 | 72 | |
| 02/07/2022 | L | at | 212 | Southern (17 - 14) | 58 | 72 | |
| 02/12/2022 | L | 347 | Arkansas Pine Bluff (7 - 24) | 70 | 75 | ||
| 02/14/2022 | L | 356 | Mississippi Valley St. (2 - 26) | 71 | 85 | ||
| 02/19/2022 | L | at | 278 | Florida A&M (13 - 17) | 83 | 86 | |
| 02/21/2022 | W | at | 337 | Bethune Cookman (9 - 21) | 89 | 78 | |
| 02/26/2022 | L | at | 292 | Alabama A&M (12 - 18) | 65 | 80 | |
| 03/03/2022 | W | 212 | Southern (17 - 14) | 77 | 67 | ||
| 03/05/2022 | W | 294 | Grambling St. (12 - 20) | 78 | 75 |