| Team: | Bethune Cookman | Rating: | -8.8276 | Average Socre: | 63.3667 |
| Conference: | Southwestern | ||||
| Wins: | 9 | Losses: | 21 | Div 1 Games: | 29 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 295 | South Florida (8 - 23) | 54 | 75 | |
| 11/12/2021 | L | at | 62 | Middle Tennessee (23 - 10) | 51 | 71 | |
| 11/15/2021 | L | at | 262 | Utah (11 - 20) | 55 | 86 | |
| 11/20/2021 | W | 102 | Bryant (22 - 9) | 81 | 75 | Daytona Beach, FL | |
| 11/21/2021 | L | at | 240 | Air Force (11 - 18) | 65 | 73 | Daytona Beach, FL |
| 11/23/2021 | L | 107 | Liberty (22 - 11) | 51 | 59 | ||
| 11/28/2021 | L | at | 59 | Seton Hall (21 - 10) | 70 | 84 | |
| 12/05/2021 | L | at | 117 | UCF (18 - 12) | 45 | 81 | |
| 12/09/2021 | L | at | 249 | N.C. State (11 - 21) | 48 | 65 | |
| 12/15/2021 | W | Johnson FL ( - ) | 88 | 41 | |||
| 12/22/2021 | L | at | 207 | Marist (14 - 16) | 45 | 68 | |
| 01/03/2022 | W | 278 | Florida A&M (13 - 17) | 66 | 59 | ||
| 01/05/2022 | L | at | 250 | FIU (15 - 17) | 65 | 68 | |
| 01/08/2022 | L | 294 | Grambling St. (12 - 20) | 66 | 68 | ||
| 01/10/2022 | L | 212 | Southern (17 - 14) | 59 | 69 | ||
| 01/15/2022 | W | at | 356 | Mississippi Valley St. (2 - 26) | 62 | 60 | |
| 01/17/2022 | L | at | 347 | Arkansas Pine Bluff (7 - 24) | 63 | 69 | |
| 01/22/2022 | W | 299 | Jackson St. (11 - 19) | 55 | 50 | ||
| 01/24/2022 | L | 213 | Alcorn St. (17 - 16) | 67 | 70 | ||
| 01/29/2022 | L | at | 328 | Alabama St. (10 - 21) | 73 | 79 | Mobile, AL |
| 01/31/2022 | L | at | 292 | Alabama A&M (12 - 18) | 52 | 67 | |
| 02/05/2022 | W | 305 | Prairie View A&M (8 - 19) | 68 | 67 | ||
| 02/07/2022 | L | 187 | Texas Southern (18 - 12) | 63 | 66 | ||
| 02/12/2022 | W | at | 213 | Alcorn St. (17 - 16) | 71 | 63 | |
| 02/14/2022 | L | at | 299 | Jackson St. (11 - 19) | 51 | 71 | |
| 02/19/2022 | L | 292 | Alabama A&M (12 - 18) | 60 | 62 | ||
| 02/21/2022 | L | 328 | Alabama St. (10 - 21) | 78 | 89 | ||
| 02/26/2022 | W | at | 212 | Southern (17 - 14) | 87 | 84 | |
| 02/28/2022 | W | at | 294 | Grambling St. (12 - 20) | 69 | 63 | |
| 03/05/2022 | L | at | 278 | Florida A&M (13 - 17) | 73 | 84 |