| Team: | Eastern Kentucky | Rating: | -5.8148 | Average Socre: | 79.2581 |
| Conference: | Atlantic Sun | ||||
| Wins: | 13 | Losses: | 18 | Div 1 Games: | 27 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | Georgetown KY ( - ) | 93 | 63 | |||
| 11/11/2021 | W | Ohio Valley ( - ) | 103 | 74 | |||
| 11/13/2021 | W | at | 311 | Milwaukee (10 - 22) | 77 | 71 | |
| 11/16/2021 | L | 182 | James Madison (15 - 14) | 78 | 79 | ||
| 11/20/2021 | W | 253 | Albany (13 - 18) | 77 | 64 | ||
| 11/22/2021 | W | 354 | Eastern Illinois (5 - 26) | 82 | 43 | ||
| 11/26/2021 | L | at | 130 | West Virginia (16 - 17) | 77 | 80 | |
| 11/28/2021 | L | at | 287 | Radford (11 - 18) | 75 | 88 | |
| 12/04/2021 | L | at | 144 | Western Kentucky (19 - 13) | 80 | 85 | |
| 12/07/2021 | L | at | 32 | USC (26 - 7) | 68 | 80 | |
| 12/11/2021 | L | 261 | Marshall (12 - 21) | 69 | 80 | ||
| 12/15/2021 | W | Midway ( - ) | 121 | 67 | |||
| 12/18/2021 | W | 148 | Northern Kentucky (20 - 12) | 81 | 68 | ||
| 12/31/2021 | W | Alice Lloyd ( - ) | 106 | 52 | |||
| 01/04/2022 | L | 279 | Central Arkansas (11 - 20) | 72 | 79 | ||
| 01/08/2022 | L | at | 127 | Bellarmine (20 - 13) | 61 | 66 | |
| 01/11/2022 | L | at | 338 | North Alabama (9 - 21) | 75 | 76 | |
| 01/15/2022 | L | 98 | Jacksonville St. (21 - 10) | 65 | 76 | ||
| 01/18/2022 | W | 263 | Lipscomb (14 - 19) | 86 | 72 | ||
| 01/22/2022 | W | 285 | North Florida (11 - 20) | 67 | 58 | ||
| 01/27/2022 | L | at | 115 | Florida Gulf Coast (21 - 11) | 73 | 77 | |
| 01/29/2022 | L | at | 312 | Stetson (11 - 19) | 95 | 113 | |
| 02/03/2022 | W | 274 | Kennesaw St. (13 - 18) | 82 | 81 | ||
| 02/05/2022 | L | 107 | Liberty (22 - 11) | 84 | 91 | ||
| 02/09/2022 | L | at | 137 | Jacksonville (21 - 10) | 68 | 81 | |
| 02/12/2022 | L | at | 263 | Lipscomb (14 - 19) | 73 | 83 | |
| 02/16/2022 | W | 338 | North Alabama (9 - 21) | 80 | 76 | ||
| 02/19/2022 | L | at | 279 | Central Arkansas (11 - 20) | 76 | 83 | |
| 02/23/2022 | L | at | 98 | Jacksonville St. (21 - 10) | 68 | 81 | |
| 02/26/2022 | W | 127 | Bellarmine (20 - 13) | 72 | 58 | ||
| 03/01/2022 | L | at | 274 | Kennesaw St. (13 - 18) | 73 | 82 |