| Team: | Virginia Tech | Rating: | 6.3714 | Average Socre: | 70.7429 |
| Conference: | ACC | ||||
| Wins: | 23 | Losses: | 12 | Div 1 Games: | 35 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | 352 | Maine (6 - 23) | 82 | 47 | ||
| 11/12/2021 | W | at | 121 | Navy (21 - 11) | 77 | 57 | |
| 11/15/2021 | W | 287 | Radford (11 - 18) | 65 | 39 | ||
| 11/18/2021 | W | 321 | St. Francis PA (9 - 21) | 85 | 55 | ||
| 11/21/2021 | W | 231 | Merrimack (14 - 16) | 72 | 43 | ||
| 11/24/2021 | L | 45 | Memphis (21 - 10) | 61 | 69 | Brooklyn, NY | |
| 11/26/2021 | L | 83 | Xavier (18 - 13) | 58 | 59 | Brooklyn, NY | |
| 12/01/2021 | W | at | 163 | Maryland (15 - 17) | 62 | 58 | |
| 12/04/2021 | L | 66 | Wake Forest (23 - 9) | 61 | 80 | ||
| 12/08/2021 | W | 178 | Cornell (15 - 11) | 93 | 60 | ||
| 12/12/2021 | L | at | 52 | Dayton (23 - 10) | 57 | 62 | |
| 12/17/2021 | W | 48 | St. Bonaventure (20 - 9) | 86 | 49 | Charlotte, NC | |
| 12/22/2021 | L | at | 8 | Duke (28 - 6) | 65 | 76 | |
| 01/04/2022 | L | 249 | N.C. State (11 - 21) | 63 | 68 | ||
| 01/12/2022 | L | at | 100 | Virginia (19 - 13) | 52 | 54 | |
| 01/15/2022 | W | 61 | Notre Dame (22 - 10) | 79 | 73 | ||
| 01/19/2022 | W | at | 249 | N.C. State (11 - 21) | 62 | 59 | |
| 01/22/2022 | L | at | 251 | Boston College (13 - 20) | 63 | 68 | |
| 01/24/2022 | L | at | 37 | North Carolina (24 - 9) | 68 | 78 | |
| 01/26/2022 | L | 46 | Miami FL (23 - 10) | 75 | 78 | ||
| 01/29/2022 | W | at | 133 | Florida St. (17 - 14) | 85 | 72 | |
| 02/02/2022 | W | 266 | Georgia Tech (12 - 20) | 81 | 66 | ||
| 02/05/2022 | W | at | 245 | Pittsburgh (11 - 21) | 76 | 71 | |
| 02/07/2022 | W | 245 | Pittsburgh (11 - 21) | 74 | 47 | ||
| 02/12/2022 | W | 164 | Syracuse (16 - 17) | 71 | 59 | ||
| 02/14/2022 | W | 100 | Virginia (19 - 13) | 62 | 53 | ||
| 02/19/2022 | L | 37 | North Carolina (24 - 9) | 57 | 65 | ||
| 02/23/2022 | W | at | 266 | Georgia Tech (12 - 20) | 62 | 58 | |
| 02/26/2022 | W | at | 46 | Miami FL (23 - 10) | 71 | 70 | |
| 03/01/2022 | W | 210 | Louisville (13 - 19) | 75 | 43 | ||
| 03/05/2022 | L | at | 156 | Clemson (17 - 16) | 59 | 63 | |
| 03/09/2022 | W | 156 | Clemson (17 - 16) | 76 | 75 | Brooklyn, NY | |
| 03/10/2022 | W | at | 61 | Notre Dame (22 - 10) | 87 | 80 | Brooklyn, NY |
| 03/11/2022 | W | at | 37 | North Carolina (24 - 9) | 72 | 59 | Brooklyn, NY |
| 03/12/2022 | W | at | 8 | Duke (28 - 6) | 82 | 67 | Brooklyn, NY |