| Team: | Xavier | Rating: | 5.5806 | Average Socre: | 73.9355 |
| Conference: | Big East | ||||
| Wins: | 18 | Losses: | 13 | Div 1 Games: | 31 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | 211 | Niagara (14 - 16) | 63 | 60 | ||
| 11/12/2021 | W | 73 | Kent St. (23 - 10) | 73 | 59 | ||
| 11/18/2021 | W | 76 | Ohio St. (19 - 11) | 71 | 65 | ||
| 11/21/2021 | W | 86 | Norfolk St. (24 - 6) | 88 | 48 | ||
| 11/24/2021 | L | 81 | Iowa St. (20 - 12) | 70 | 82 | Brooklyn, NY | |
| 11/26/2021 | W | at | 68 | Virginia Tech (23 - 12) | 59 | 58 | Brooklyn, NY |
| 12/01/2021 | W | 310 | Central Michigan (7 - 23) | 78 | 45 | ||
| 12/05/2021 | W | at | 126 | Oklahoma St. (15 - 15) | 77 | 71 | |
| 12/08/2021 | W | 229 | Ball St. (14 - 17) | 96 | 50 | ||
| 12/11/2021 | W | 157 | Cincinnati (18 - 15) | 83 | 63 | ||
| 12/15/2021 | W | 96 | Morehead St. (23 - 11) | 86 | 63 | ||
| 12/18/2021 | W | 78 | Marquette (19 - 12) | 80 | 71 | ||
| 12/21/2021 | L | at | 14 | Villanova (26 - 7) | 58 | 71 | |
| 01/07/2022 | W | at | 205 | Butler (14 - 19) | 87 | 72 | |
| 01/12/2022 | L | 14 | Villanova (26 - 7) | 60 | 64 | ||
| 01/15/2022 | W | 51 | Creighton (22 - 11) | 80 | 73 | ||
| 01/19/2022 | W | at | 172 | DePaul (15 - 16) | 68 | 67 | |
| 01/23/2022 | L | at | 78 | Marquette (19 - 12) | 64 | 75 | |
| 01/26/2022 | L | 10 | Providence (25 - 5) | 62 | 65 | ||
| 01/29/2022 | W | at | 51 | Creighton (22 - 11) | 74 | 64 | |
| 02/02/2022 | W | 205 | Butler (14 - 19) | 68 | 66 | ||
| 02/05/2022 | L | 172 | DePaul (15 - 16) | 65 | 69 | ||
| 02/09/2022 | L | at | 59 | Seton Hall (21 - 10) | 71 | 73 | |
| 02/11/2022 | W | 40 | Connecticut (23 - 9) | 74 | 68 | ||
| 02/16/2022 | L | 143 | St. John's (17 - 15) | 73 | 86 | ||
| 02/19/2022 | L | at | 40 | Connecticut (23 - 9) | 61 | 72 | |
| 02/23/2022 | L | at | 10 | Providence (25 - 5) | 92 | 99 | |
| 02/26/2022 | L | 59 | Seton Hall (21 - 10) | 66 | 82 | ||
| 03/02/2022 | L | at | 143 | St. John's (17 - 15) | 66 | 81 | |
| 03/05/2022 | W | 303 | Georgetown (6 - 25) | 97 | 75 | ||
| 03/09/2022 | L | 205 | Butler (14 - 19) | 82 | 89 | New York, NY |