| Team: | DePaul | Rating: | 1.55556 | Average Socre: | 78.3611 |
| Conference: | Big East | ||||
| Wins: | 19 | Losses: | 17 | Div 1 Games: | 36 |
| Date | Rnk | Team | Location | ||||
| 11/07/2018 | W | 271 | Bethune Cookman (14 - 17) | 80 | 58 | ||
| 11/12/2018 | W | 335 | Morgan St. (9 - 21) | 91 | 63 | ||
| 11/15/2018 | W | 151 | Penn St. (14 - 18) | 72 | 70 | ||
| 11/24/2018 | L | at | 205 | Notre Dame (14 - 19) | 70 | 95 | |
| 11/28/2018 | W | 312 | Cleveland St. (10 - 21) | 83 | 73 | ||
| 12/03/2018 | W | 305 | Florida A&M (12 - 19) | 65 | 50 | ||
| 12/08/2018 | L | at | 225 | Northwestern (13 - 19) | 68 | 75 | |
| 12/12/2018 | W | 353 | Chicago St. (3 - 29) | 104 | 70 | ||
| 12/14/2018 | W | 220 | Illinois Chicago (16 - 16) | 90 | 70 | ||
| 12/19/2018 | W | 346 | Incarnate Word (6 - 25) | 81 | 71 | ||
| 12/22/2018 | L | 187 | Boston College (14 - 17) | 62 | 65 | ||
| 12/29/2018 | L | 111 | Xavier (19 - 16) | 65 | 74 | ||
| 01/02/2019 | L | at | 30 | Villanova (26 - 10) | 68 | 73 | |
| 01/06/2019 | W | 73 | Seton Hall (20 - 14) | 75 | 74 | ||
| 01/12/2019 | W | at | 80 | St. John's (21 - 13) | 79 | 71 | |
| 01/16/2019 | L | 136 | Butler (16 - 17) | 69 | 87 | ||
| 01/19/2019 | W | at | 73 | Seton Hall (20 - 14) | 97 | 93 | |
| 01/23/2019 | L | at | 33 | Marquette (24 - 10) | 69 | 79 | |
| 01/27/2019 | L | at | 122 | Providence (18 - 16) | 67 | 70 | |
| 01/30/2019 | L | 30 | Villanova (26 - 10) | 74 | 86 | ||
| 02/02/2019 | W | 122 | Providence (18 - 16) | 67 | 55 | ||
| 02/09/2019 | W | at | 111 | Xavier (19 - 16) | 74 | 62 | |
| 02/12/2019 | L | 33 | Marquette (24 - 10) | 73 | 92 | ||
| 02/16/2019 | L | at | 136 | Butler (16 - 17) | 78 | 91 | |
| 02/20/2019 | L | 91 | Creighton (20 - 15) | 67 | 79 | ||
| 02/27/2019 | L | at | 100 | Georgetown (19 - 14) | 73 | 82 | |
| 03/03/2019 | W | 80 | St. John's (21 - 13) | 92 | 83 | ||
| 03/06/2019 | W | 100 | Georgetown (19 - 14) | 101 | 69 | ||
| 03/09/2019 | L | at | 91 | Creighton (20 - 15) | 78 | 91 | |
| 03/13/2019 | L | at | 80 | St. John's (21 - 13) | 74 | 82 | New York, NY |
| 03/20/2019 | W | 101 | Central Michigan (23 - 12) | 100 | 86 | ||
| 03/25/2019 | W | 263 | Longwood (16 - 18) | 97 | 89 | ||
| 03/27/2019 | W | 192 | Coastal Carolina (17 - 17) | 92 | 87 | ||
| 04/01/2019 | L | at | 85 | South Florida (24 - 14) | 61 | 63 | |
| 04/03/2019 | W | 85 | South Florida (24 - 14) | 100 | 96 | ||
| 04/05/2019 | L | 85 | South Florida (24 - 14) | 65 | 77 |