| Team: | Oklahoma St. | Rating: | 3.1333 | Average Socre: | 68.3667 |
| Conference: | Big 12 | ||||
| Wins: | 15 | Losses: | 15 | Div 1 Games: | 30 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | 257 | UT Arlington (11 - 18) | 88 | 45 | ||
| 11/12/2021 | L | 125 | Oakland (20 - 12) | 55 | 56 | ||
| 11/14/2021 | W | 305 | Prairie View A&M (8 - 19) | 72 | 59 | ||
| 11/16/2021 | W | 230 | UMass Lowell (15 - 16) | 80 | 58 | Uncasville, CT | |
| 11/17/2021 | W | 249 | N.C. State (11 - 21) | 74 | 68 | Uncasville, CT | |
| 11/22/2021 | W | 160 | Charleston (17 - 15) | 96 | 66 | ||
| 11/26/2021 | W | at | 154 | Oral Roberts (19 - 12) | 78 | 77 | |
| 12/01/2021 | L | 128 | Wichita St. (15 - 13) | 51 | 60 | ||
| 12/05/2021 | L | 83 | Xavier (18 - 13) | 71 | 77 | ||
| 12/13/2021 | W | 111 | Cleveland St. (20 - 10) | 98 | 93 | ||
| 12/18/2021 | L | 7 | Houston (29 - 5) | 61 | 72 | Fort Worth, TX | |
| 01/04/2022 | L | 4 | Kansas (28 - 6) | 63 | 74 | ||
| 01/08/2022 | W | 55 | Texas (21 - 11) | 64 | 51 | ||
| 01/11/2022 | L | at | 130 | West Virginia (16 - 17) | 60 | 70 | |
| 01/13/2022 | L | at | 31 | Texas Tech (25 - 9) | 57 | 78 | |
| 01/15/2022 | W | at | 12 | Baylor (26 - 6) | 61 | 54 | |
| 01/19/2022 | W | 72 | TCU (20 - 12) | 57 | 56 | ||
| 01/22/2022 | L | at | 55 | Texas (21 - 11) | 51 | 56 | |
| 01/26/2022 | L | 81 | Iowa St. (20 - 12) | 81 | 84 | ||
| 01/29/2022 | L | at | 106 | Florida (19 - 13) | 72 | 81 | |
| 02/02/2022 | L | at | 192 | Kansas St. (14 - 17) | 68 | 71 | |
| 02/05/2022 | W | 103 | Oklahoma (18 - 15) | 64 | 55 | ||
| 02/08/2022 | L | at | 72 | TCU (20 - 12) | 73 | 77 | |
| 02/12/2022 | W | 130 | West Virginia (16 - 17) | 81 | 58 | ||
| 02/14/2022 | L | at | 4 | Kansas (28 - 6) | 62 | 76 | |
| 02/19/2022 | W | 192 | Kansas St. (14 - 17) | 82 | 79 | ||
| 02/21/2022 | L | 12 | Baylor (26 - 6) | 64 | 66 | ||
| 02/26/2022 | L | at | 103 | Oklahoma (18 - 15) | 62 | 66 | |
| 03/02/2022 | W | at | 81 | Iowa St. (20 - 12) | 53 | 36 | |
| 03/05/2022 | W | 31 | Texas Tech (25 - 9) | 52 | 51 |