| Team: | Central Michigan | Rating: | -6.9333 | Average Socre: | 65.9333 |
| Conference: | Mid American | ||||
| Wins: | 7 | Losses: | 23 | Div 1 Games: | 30 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 238 | Missouri (12 - 21) | 68 | 78 | |
| 11/13/2021 | L | at | 172 | DePaul (15 - 16) | 66 | 99 | |
| 11/15/2021 | W | at | 354 | Eastern Illinois (5 - 26) | 62 | 61 | |
| 11/22/2021 | L | at | 1 | Gonzaga (26 - 3) | 54 | 107 | Las Vegas, NV |
| 11/23/2021 | L | 127 | Bellarmine (20 - 13) | 69 | 76 | Las Vegas, NV | |
| 11/29/2021 | L | at | 13 | Kentucky (26 - 7) | 57 | 85 | |
| 12/01/2021 | L | at | 83 | Xavier (18 - 13) | 45 | 78 | |
| 12/05/2021 | L | 217 | Western Illinois (16 - 15) | 70 | 97 | ||
| 12/08/2021 | L | at | 214 | Youngstown St. (18 - 14) | 77 | 84 | |
| 12/11/2021 | L | 247 | Illinois Chicago (14 - 16) | 67 | 71 | ||
| 12/19/2021 | L | at | 215 | Detroit Mercy (14 - 15) | 75 | 89 | |
| 12/29/2021 | W | at | 73 | Kent St. (23 - 10) | 72 | 69 | |
| 01/04/2022 | L | 42 | Toledo (26 - 7) | 54 | 82 | ||
| 01/11/2022 | L | at | 300 | Eastern Michigan (10 - 21) | 68 | 99 | |
| 01/25/2022 | L | 74 | Akron (24 - 9) | 56 | 60 | ||
| 01/29/2022 | W | at | 293 | Northern Illinois (9 - 21) | 69 | 63 | |
| 02/01/2022 | W | 264 | Bowling Green (13 - 18) | 78 | 74 | ||
| 02/03/2022 | W | 316 | Western Michigan (8 - 23) | 65 | 55 | ||
| 02/05/2022 | L | 114 | Buffalo (19 - 11) | 54 | 74 | ||
| 02/08/2022 | W | at | 229 | Ball St. (14 - 17) | 89 | 85 | |
| 02/10/2022 | L | 65 | Ohio (24 - 9) | 72 | 81 | ||
| 02/12/2022 | L | at | 316 | Western Michigan (8 - 23) | 63 | 77 | |
| 02/15/2022 | L | 300 | Eastern Michigan (10 - 21) | 70 | 75 | ||
| 02/19/2022 | L | at | 42 | Toledo (26 - 7) | 66 | 68 | |
| 02/22/2022 | L | at | 65 | Ohio (24 - 9) | 50 | 76 | |
| 02/24/2022 | W | at | 276 | Miami OH (14 - 18) | 83 | 69 | |
| 02/26/2022 | L | 73 | Kent St. (23 - 10) | 71 | 73 | ||
| 03/01/2022 | L | 276 | Miami OH (14 - 18) | 61 | 75 | ||
| 03/04/2022 | L | at | 74 | Akron (24 - 9) | 56 | 57 | |
| 03/10/2022 | L | at | 42 | Toledo (26 - 7) | 71 | 72 | Cleveland, OH |