| Team: | St. John's | Rating: | 2.625 | Average Socre: | 79.5938 |
| Conference: | Big East | ||||
| Wins: | 17 | Losses: | 15 | Div 1 Games: | 32 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | 356 | Mississippi Valley St. (2 - 26) | 119 | 61 | ||
| 11/13/2021 | W | 95 | Saint Peter's (19 - 11) | 91 | 70 | ||
| 11/17/2021 | L | at | 92 | Indiana (20 - 13) | 74 | 76 | |
| 11/20/2021 | W | 350 | Fairleigh Dickinson (4 - 22) | 87 | 74 | ||
| 11/23/2021 | W | 326 | St. Francis NY (10 - 20) | 76 | 70 | ||
| 11/27/2021 | W | 283 | NJIT (11 - 18) | 77 | 68 | ||
| 12/03/2021 | L | 4 | Kansas (28 - 6) | 75 | 95 | Elmont, NY | |
| 12/05/2021 | W | 190 | Fordham (16 - 16) | 83 | 69 | ||
| 12/09/2021 | W | 94 | Monmouth (21 - 13) | 88 | 83 | ||
| 12/12/2021 | W | 118 | Colgate (23 - 11) | 82 | 64 | ||
| 12/18/2021 | L | 245 | Pittsburgh (11 - 21) | 57 | 59 | ||
| 01/05/2022 | W | 172 | DePaul (15 - 16) | 89 | 84 | ||
| 01/08/2022 | L | at | 10 | Providence (25 - 5) | 73 | 83 | |
| 01/12/2022 | L | at | 40 | Connecticut (23 - 9) | 78 | 86 | |
| 01/16/2022 | W | 303 | Georgetown (6 - 25) | 88 | 69 | ||
| 01/19/2022 | L | at | 51 | Creighton (22 - 11) | 64 | 87 | |
| 01/22/2022 | L | 59 | Seton Hall (21 - 10) | 60 | 66 | ||
| 01/24/2022 | W | at | 59 | Seton Hall (21 - 10) | 84 | 63 | |
| 01/29/2022 | L | at | 14 | Villanova (26 - 7) | 62 | 73 | |
| 02/01/2022 | L | 10 | Providence (25 - 5) | 82 | 86 | ||
| 02/03/2022 | W | at | 303 | Georgetown (6 - 25) | 90 | 77 | |
| 02/05/2022 | W | at | 205 | Butler (14 - 19) | 75 | 72 | |
| 02/08/2022 | L | 14 | Villanova (26 - 7) | 69 | 75 | ||
| 02/13/2022 | L | 40 | Connecticut (23 - 9) | 60 | 63 | ||
| 02/16/2022 | W | at | 83 | Xavier (18 - 13) | 86 | 73 | |
| 02/18/2022 | W | 205 | Butler (14 - 19) | 91 | 57 | ||
| 02/23/2022 | L | 51 | Creighton (22 - 11) | 78 | 81 | ||
| 02/27/2022 | L | at | 172 | DePaul (15 - 16) | 94 | 99 | |
| 03/02/2022 | W | 83 | Xavier (18 - 13) | 81 | 66 | ||
| 03/05/2022 | L | at | 78 | Marquette (19 - 12) | 77 | 85 | |
| 03/09/2022 | W | 172 | DePaul (15 - 16) | 92 | 73 | New York, NY | |
| 03/10/2022 | L | 14 | Villanova (26 - 7) | 65 | 66 | New York, NY |