| Team: | Eastern Illinois | Rating: | -13.2759 | Average Socre: | 56.3226 |
| Conference: | Ohio Valley | ||||
| Wins: | 5 | Losses: | 26 | Div 1 Games: | 29 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 193 | Northwestern (15 - 16) | 56 | 80 | |
| 11/12/2021 | L | at | 50 | Saint Louis (23 - 11) | 44 | 86 | |
| 11/15/2021 | L | 310 | Central Michigan (7 - 23) | 61 | 62 | ||
| 11/18/2021 | W | Rockford ( - ) | 96 | 64 | |||
| 11/22/2021 | L | at | 298 | Eastern Kentucky (13 - 18) | 43 | 82 | |
| 11/24/2021 | L | at | 253 | Albany (13 - 18) | 62 | 64 | Richmond, KY |
| 11/28/2021 | L | 342 | Evansville (6 - 24) | 54 | 70 | ||
| 12/01/2021 | L | at | 293 | Northern Illinois (9 - 21) | 45 | 55 | |
| 12/04/2021 | W | North Park ( - ) | 76 | 71 | |||
| 12/07/2021 | L | at | 238 | Missouri (12 - 21) | 44 | 72 | |
| 12/11/2021 | L | at | 205 | Butler (14 - 19) | 54 | 66 | |
| 12/18/2021 | L | at | 217 | Western Illinois (16 - 15) | 54 | 71 | |
| 12/21/2021 | L | at | 229 | Ball St. (14 - 17) | 55 | 75 | |
| 12/29/2021 | L | at | 96 | Morehead St. (23 - 11) | 50 | 63 | |
| 01/13/2022 | L | 302 | SIU Edwardsville (11 - 21) | 53 | 66 | ||
| 01/17/2022 | L | 3 | Murray St. (30 - 2) | 46 | 72 | ||
| 01/20/2022 | L | at | 3 | Murray St. (30 - 2) | 51 | 91 | |
| 01/22/2022 | L | 234 | Southeast Missouri St. (14 - 18) | 58 | 87 | ||
| 01/24/2022 | L | 33 | Belmont (25 - 7) | 56 | 90 | ||
| 01/27/2022 | W | at | 332 | Tennessee Martin (8 - 22) | 58 | 53 | |
| 01/29/2022 | W | 277 | Tennessee St. (14 - 18) | 62 | 57 | ||
| 02/05/2022 | L | at | 234 | Southeast Missouri St. (14 - 18) | 56 | 63 | |
| 02/07/2022 | L | at | 291 | Tennessee Tech (11 - 21) | 58 | 84 | |
| 02/10/2022 | L | 291 | Tennessee Tech (11 - 21) | 62 | 73 | ||
| 02/12/2022 | W | 332 | Tennessee Martin (8 - 22) | 82 | 70 | ||
| 02/14/2022 | L | at | 275 | Austin Peay (12 - 17) | 54 | 62 | |
| 02/17/2022 | L | at | 33 | Belmont (25 - 7) | 57 | 81 | |
| 02/19/2022 | L | at | 277 | Tennessee St. (14 - 18) | 49 | 63 | |
| 02/21/2022 | L | at | 302 | SIU Edwardsville (11 - 21) | 52 | 66 | |
| 02/24/2022 | L | 96 | Morehead St. (23 - 11) | 46 | 82 | ||
| 02/26/2022 | L | 275 | Austin Peay (12 - 17) | 52 | 64 |