| Team: | Tennessee Tech | Rating: | -5.5 | Average Socre: | 72.75 |
| Conference: | Ohio Valley | ||||
| Wins: | 11 | Losses: | 21 | Div 1 Games: | 30 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 45 | Memphis (21 - 10) | 65 | 89 | |
| 11/14/2021 | W | Oakwood ( - ) | 109 | 68 | |||
| 11/16/2021 | L | at | 22 | Chattanooga (27 - 7) | 62 | 69 | |
| 11/18/2021 | L | at | 208 | UNC Asheville (16 - 14) | 55 | 61 | Chattanooga, TN |
| 11/23/2021 | W | 263 | Lipscomb (14 - 19) | 88 | 77 | ||
| 11/26/2021 | L | at | 6 | Tennessee (26 - 7) | 69 | 80 | |
| 11/30/2021 | L | 22 | Chattanooga (27 - 7) | 65 | 82 | ||
| 12/04/2021 | L | at | 342 | Evansville (6 - 24) | 51 | 59 | |
| 12/08/2021 | L | at | 273 | Western Carolina (11 - 21) | 69 | 74 | |
| 12/11/2021 | L | 120 | Troy (20 - 11) | 72 | 75 | ||
| 12/16/2021 | W | Montreat ( - ) | 117 | 60 | |||
| 12/18/2021 | L | at | 139 | Wright St. (21 - 13) | 63 | 72 | |
| 12/21/2021 | L | at | 157 | Cincinnati (18 - 15) | 67 | 76 | |
| 01/13/2022 | L | at | 33 | Belmont (25 - 7) | 77 | 92 | |
| 01/15/2022 | W | at | 332 | Tennessee Martin (8 - 22) | 76 | 70 | |
| 01/17/2022 | L | at | 277 | Tennessee St. (14 - 18) | 64 | 80 | |
| 01/20/2022 | W | 302 | SIU Edwardsville (11 - 21) | 94 | 76 | ||
| 01/24/2022 | L | at | 3 | Murray St. (30 - 2) | 53 | 79 | |
| 01/27/2022 | L | 3 | Murray St. (30 - 2) | 75 | 80 | ||
| 01/29/2022 | L | 275 | Austin Peay (12 - 17) | 55 | 58 | ||
| 01/31/2022 | L | 96 | Morehead St. (23 - 11) | 56 | 70 | ||
| 02/03/2022 | L | at | 96 | Morehead St. (23 - 11) | 68 | 75 | |
| 02/05/2022 | L | 33 | Belmont (25 - 7) | 92 | 100 | ||
| 02/07/2022 | W | 354 | Eastern Illinois (5 - 26) | 84 | 58 | ||
| 02/10/2022 | W | at | 354 | Eastern Illinois (5 - 26) | 73 | 62 | |
| 02/12/2022 | L | at | 302 | SIU Edwardsville (11 - 21) | 60 | 61 | |
| 02/17/2022 | W | 234 | Southeast Missouri St. (14 - 18) | 98 | 94 | ||
| 02/19/2022 | W | at | 275 | Austin Peay (12 - 17) | 73 | 69 | |
| 02/24/2022 | L | 277 | Tennessee St. (14 - 18) | 56 | 92 | ||
| 02/26/2022 | W | 332 | Tennessee Martin (8 - 22) | 88 | 75 | ||
| 03/02/2022 | W | at | 275 | Austin Peay (12 - 17) | 78 | 51 | Evansville, IN |
| 03/03/2022 | L | at | 96 | Morehead St. (23 - 11) | 56 | 73 | Evansville, IN |