| Team: | Northern Illinois | Rating: | -5.6 | Average Socre: | 64.1 |
| Conference: | Mid American | ||||
| Wins: | 9 | Losses: | 21 | Div 1 Games: | 30 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | at | 136 | Washington (17 - 15) | 71 | 64 | |
| 11/12/2021 | L | at | 92 | Indiana (20 - 13) | 49 | 85 | |
| 11/18/2021 | L | at | 238 | Missouri (12 - 21) | 37 | 54 | |
| 11/21/2021 | L | 158 | Boston University (21 - 12) | 58 | 76 | Jacksonville, FL | |
| 11/22/2021 | L | at | 301 | Little Rock (9 - 19) | 60 | 67 | Jacksonville, FL |
| 11/27/2021 | L | at | 78 | Marquette (19 - 12) | 66 | 80 | |
| 12/01/2021 | W | 354 | Eastern Illinois (5 - 26) | 55 | 45 | ||
| 12/04/2021 | L | at | 52 | Dayton (23 - 10) | 41 | 79 | |
| 12/13/2021 | W | at | 327 | Chicago St. (7 - 25) | 70 | 59 | |
| 12/19/2021 | L | at | 247 | Illinois Chicago (14 - 16) | 60 | 61 | |
| 01/08/2022 | L | at | 42 | Toledo (26 - 7) | 63 | 94 | |
| 01/11/2022 | W | at | 73 | Kent St. (23 - 10) | 65 | 63 | |
| 01/15/2022 | W | 300 | Eastern Michigan (10 - 21) | 77 | 70 | ||
| 01/18/2022 | L | 264 | Bowling Green (13 - 18) | 83 | 92 | ||
| 01/22/2022 | L | at | 276 | Miami OH (14 - 18) | 82 | 85 | |
| 01/25/2022 | L | at | 65 | Ohio (24 - 9) | 62 | 74 | |
| 01/27/2022 | L | 229 | Ball St. (14 - 17) | 67 | 74 | ||
| 01/29/2022 | L | 310 | Central Michigan (7 - 23) | 63 | 69 | ||
| 02/01/2022 | W | at | 316 | Western Michigan (8 - 23) | 75 | 56 | |
| 02/05/2022 | L | at | 264 | Bowling Green (13 - 18) | 65 | 87 | |
| 02/08/2022 | L | 74 | Akron (24 - 9) | 64 | 70 | ||
| 02/12/2022 | L | 42 | Toledo (26 - 7) | 72 | 100 | ||
| 02/15/2022 | W | at | 229 | Ball St. (14 - 17) | 64 | 58 | |
| 02/17/2022 | W | at | 74 | Akron (24 - 9) | 66 | 63 | |
| 02/19/2022 | L | 276 | Miami OH (14 - 18) | 75 | 78 | ||
| 02/22/2022 | L | at | 300 | Eastern Michigan (10 - 21) | 72 | 74 | |
| 02/24/2022 | L | 114 | Buffalo (19 - 11) | 68 | 79 | ||
| 02/26/2022 | L | at | 114 | Buffalo (19 - 11) | 60 | 70 | |
| 03/01/2022 | L | 73 | Kent St. (23 - 10) | 55 | 63 | ||
| 03/04/2022 | W | 65 | Ohio (24 - 9) | 58 | 57 |