| Team: | Loyola Chicago | Rating: | 9.2903 | Average Socre: | 73.8125 |
| Conference: | Missouri Valley | ||||
| Wins: | 25 | Losses: | 7 | Div 1 Games: | 31 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | 296 | Coppin St. (9 - 23) | 103 | 45 | ||
| 11/13/2021 | W | 115 | Florida Gulf Coast (21 - 11) | 89 | 77 | ||
| 11/16/2021 | W | 327 | Chicago St. (7 - 25) | 92 | 56 | ||
| 11/20/2021 | W | 247 | Illinois Chicago (14 - 16) | 80 | 63 | ||
| 11/24/2021 | L | 49 | Michigan St. (22 - 12) | 61 | 63 | Nassau, Bahamas | |
| 11/25/2021 | L | at | 5 | Auburn (27 - 5) | 53 | 62 | Nassau, Bahamas |
| 11/26/2021 | W | at | 161 | Arizona St. (14 - 17) | 77 | 59 | Nassau, Bahamas |
| 12/01/2021 | W | 297 | Indiana St. (11 - 20) | 88 | 76 | ||
| 12/04/2021 | W | at | 172 | DePaul (15 - 16) | 68 | 64 | |
| 12/07/2021 | W | Roosevelt ( - ) | 88 | 49 | |||
| 12/10/2021 | W | at | 134 | Vanderbilt (17 - 16) | 69 | 58 | |
| 01/06/2022 | W | at | 23 | San Francisco (24 - 9) | 79 | 74 | Salt Lake City, UT |
| 01/08/2022 | W | 151 | Bradley (17 - 14) | 78 | 71 | ||
| 01/11/2022 | W | 243 | Valparaiso (14 - 18) | 81 | 74 | ||
| 01/15/2022 | W | at | 297 | Indiana St. (11 - 20) | 64 | 56 | |
| 01/18/2022 | W | at | 342 | Evansville (6 - 24) | 77 | 48 | |
| 01/22/2022 | L | 57 | Missouri St. (23 - 10) | 69 | 79 | ||
| 01/25/2022 | W | 183 | Southern Illinois (16 - 15) | 59 | 47 | ||
| 01/27/2022 | W | at | 183 | Southern Illinois (16 - 15) | 44 | 39 | |
| 01/30/2022 | L | at | 70 | Drake (24 - 10) | 68 | 77 | |
| 02/02/2022 | W | 258 | Illinois St. (13 - 20) | 78 | 64 | ||
| 02/06/2022 | W | at | 57 | Missouri St. (23 - 10) | 71 | 62 | |
| 02/09/2022 | L | at | 151 | Bradley (17 - 14) | 61 | 68 | |
| 02/13/2022 | W | 82 | Northern Iowa (19 - 11) | 85 | 58 | ||
| 02/16/2022 | W | at | 243 | Valparaiso (14 - 18) | 71 | 69 | |
| 02/19/2022 | L | 70 | Drake (24 - 10) | 76 | 83 | ||
| 02/21/2022 | W | at | 258 | Illinois St. (13 - 20) | 59 | 50 | |
| 02/23/2022 | W | 342 | Evansville (6 - 24) | 82 | 31 | ||
| 02/26/2022 | L | at | 82 | Northern Iowa (19 - 11) | 96 | 102 | |
| 03/04/2022 | W | 151 | Bradley (17 - 14) | 66 | 50 | St. Louis, MO | |
| 03/05/2022 | W | at | 82 | Northern Iowa (19 - 11) | 66 | 43 | St. Louis, MO |
| 03/06/2022 | W | at | 70 | Drake (24 - 10) | 64 | 58 | St. Louis, MO |