| Team: | Indiana St. | Rating: | -5.7857 | Average Socre: | 70.4516 |
| Conference: | Missouri Valley | ||||
| Wins: | 11 | Losses: | 20 | Div 1 Games: | 28 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | at | 351 | Green Bay (5 - 25) | 81 | 77 | |
| 11/12/2021 | L | at | 15 | Purdue (27 - 7) | 67 | 92 | |
| 11/14/2021 | W | Hanover ( - ) | 90 | 49 | |||
| 11/18/2021 | W | at | 221 | Old Dominion (13 - 19) | 77 | 36 | Conway, SC |
| 11/19/2021 | L | 103 | Oklahoma (18 - 15) | 63 | 87 | Conway, SC | |
| 11/21/2021 | L | 21 | New Mexico St. (26 - 6) | 66 | 80 | Conway, SC | |
| 11/27/2021 | L | at | 229 | Ball St. (14 - 17) | 75 | 97 | |
| 12/01/2021 | L | at | 34 | Loyola Chicago (25 - 7) | 76 | 88 | |
| 12/04/2021 | W | 276 | Miami OH (14 - 18) | 69 | 68 | ||
| 12/13/2021 | L | at | 88 | North Dakota St. (23 - 10) | 70 | 77 | |
| 12/18/2021 | W | 292 | Alabama A&M (12 - 18) | 67 | 43 | ||
| 12/20/2021 | W | Oakland City ( - ) | 78 | 69 | |||
| 12/29/2021 | W | Midway ( - ) | 107 | 51 | |||
| 01/02/2022 | W | 151 | Bradley (17 - 14) | 76 | 71 | ||
| 01/11/2022 | L | at | 82 | Northern Iowa (19 - 11) | 74 | 80 | |
| 01/15/2022 | L | 34 | Loyola Chicago (25 - 7) | 56 | 64 | ||
| 01/19/2022 | L | at | 183 | Southern Illinois (16 - 15) | 55 | 63 | |
| 01/22/2022 | L | 243 | Valparaiso (14 - 18) | 73 | 75 | ||
| 01/25/2022 | W | 57 | Missouri St. (23 - 10) | 76 | 72 | ||
| 01/30/2022 | L | at | 151 | Bradley (17 - 14) | 52 | 67 | |
| 02/02/2022 | L | 70 | Drake (24 - 10) | 67 | 85 | ||
| 02/05/2022 | L | at | 243 | Valparaiso (14 - 18) | 72 | 79 | |
| 02/08/2022 | L | 342 | Evansville (6 - 24) | 56 | 65 | ||
| 02/10/2022 | W | at | 342 | Evansville (6 - 24) | 80 | 77 | |
| 02/12/2022 | W | 258 | Illinois St. (13 - 20) | 60 | 57 | ||
| 02/15/2022 | L | at | 57 | Missouri St. (23 - 10) | 70 | 79 | |
| 02/19/2022 | L | 183 | Southern Illinois (16 - 15) | 72 | 76 | ||
| 02/21/2022 | L | at | 70 | Drake (24 - 10) | 58 | 74 | |
| 02/23/2022 | L | 82 | Northern Iowa (19 - 11) | 82 | 88 | ||
| 02/26/2022 | L | at | 258 | Illinois St. (13 - 20) | 66 | 86 | |
| 03/03/2022 | L | at | 258 | Illinois St. (13 - 20) | 53 | 58 | St. Louis, MO |