| Team: | USC | Rating: | 9.4242 | Average Socre: | 72.5758 |
| Conference: | PAC 12 | ||||
| Wins: | 26 | Losses: | 7 | Div 1 Games: | 33 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | 309 | Cal St. Northridge (7 - 23) | 89 | 49 | ||
| 11/13/2021 | W | at | 124 | Temple (17 - 12) | 76 | 71 | |
| 11/16/2021 | W | at | 115 | Florida Gulf Coast (21 - 11) | 78 | 61 | |
| 11/22/2021 | W | 232 | Dixie St. (13 - 18) | 98 | 71 | ||
| 11/25/2021 | W | 246 | Saint Joseph's (11 - 19) | 70 | 55 | Anaheim, CA | |
| 11/26/2021 | W | at | 26 | San Diego St. (23 - 8) | 58 | 43 | Anaheim, CA |
| 12/01/2021 | W | 262 | Utah (11 - 20) | 93 | 73 | ||
| 12/04/2021 | W | at | 99 | Washington St. (19 - 14) | 63 | 61 | |
| 12/07/2021 | W | 298 | Eastern Kentucky (13 - 18) | 80 | 68 | ||
| 12/12/2021 | W | 104 | Long Beach St. (20 - 12) | 73 | 62 | ||
| 12/15/2021 | W | 146 | UC Irvine (15 - 10) | 66 | 61 | ||
| 12/18/2021 | W | 266 | Georgia Tech (12 - 20) | 67 | 53 | Phoenix, AZ | |
| 01/06/2022 | W | at | 237 | California (12 - 20) | 77 | 63 | |
| 01/11/2022 | L | at | 147 | Stanford (16 - 16) | 69 | 75 | |
| 01/13/2022 | W | 344 | Oregon St. (3 - 28) | 81 | 71 | ||
| 01/15/2022 | L | 112 | Oregon (19 - 14) | 69 | 79 | ||
| 01/20/2022 | W | at | 79 | Colorado (21 - 11) | 61 | 58 | |
| 01/22/2022 | W | at | 262 | Utah (11 - 20) | 79 | 67 | |
| 01/24/2022 | W | 161 | Arizona St. (14 - 17) | 78 | 56 | ||
| 01/27/2022 | L | 147 | Stanford (16 - 16) | 61 | 64 | ||
| 01/29/2022 | W | 237 | California (12 - 20) | 79 | 72 | ||
| 02/03/2022 | W | at | 161 | Arizona St. (14 - 17) | 58 | 53 | |
| 02/05/2022 | L | at | 2 | Arizona (31 - 3) | 63 | 72 | |
| 02/08/2022 | W | 333 | Pacific (8 - 22) | 74 | 68 | ||
| 02/12/2022 | W | 16 | UCLA (25 - 7) | 67 | 64 | ||
| 02/17/2022 | W | 136 | Washington (17 - 15) | 79 | 69 | ||
| 02/20/2022 | W | 99 | Washington St. (19 - 14) | 62 | 60 | ||
| 02/24/2022 | W | at | 344 | Oregon St. (3 - 28) | 94 | 91 | |
| 02/26/2022 | W | at | 112 | Oregon (19 - 14) | 70 | 69 | |
| 03/01/2022 | L | 2 | Arizona (31 - 3) | 71 | 91 | ||
| 03/05/2022 | L | at | 16 | UCLA (25 - 7) | 68 | 75 | |
| 03/10/2022 | W | 136 | Washington (17 - 15) | 65 | 61 | Las Vegas, NV | |
| 03/11/2022 | L | at | 16 | UCLA (25 - 7) | 59 | 69 | Las Vegas, NV |