| Team: | UMass Lowell | Rating: | -2.5714 | Average Socre: | 70.6774 |
| Conference: | American East | ||||
| Wins: | 15 | Losses: | 16 | Div 1 Games: | 28 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | Rivier ( - ) | 91 | 55 | |||
| 11/13/2021 | W | at | 52 | Dayton (23 - 10) | 59 | 58 | |
| 11/16/2021 | L | at | 126 | Oklahoma St. (15 - 15) | 58 | 80 | Uncasville, CT |
| 11/17/2021 | W | at | 336 | Central Connecticut (8 - 24) | 77 | 53 | Uncasville, CT |
| 11/19/2021 | W | at | 236 | George Washington (12 - 18) | 67 | 56 | |
| 11/24/2021 | L | at | 195 | Massachusetts (15 - 17) | 81 | 92 | |
| 11/27/2021 | W | Fisher ( - ) | 101 | 38 | |||
| 12/01/2021 | L | 224 | Brown (13 - 16) | 63 | 73 | ||
| 12/04/2021 | W | at | 231 | Merrimack (14 - 16) | 61 | 57 | |
| 12/08/2021 | L | at | 158 | Boston University (21 - 12) | 62 | 72 | |
| 12/11/2021 | W | Mass College of Libera ( - ) | 109 | 45 | |||
| 12/19/2021 | W | 319 | Sacred Heart (10 - 20) | 70 | 62 | ||
| 01/02/2022 | L | at | 267 | Binghamton (12 - 17) | 63 | 68 | |
| 01/06/2022 | L | 283 | NJIT (11 - 18) | 72 | 77 | ||
| 01/08/2022 | W | at | 176 | UMBC (18 - 14) | 66 | 64 | |
| 01/12/2022 | L | at | 253 | Albany (13 - 18) | 47 | 57 | |
| 01/19/2022 | W | 352 | Maine (6 - 23) | 71 | 62 | ||
| 01/22/2022 | L | at | 204 | New Hampshire (15 - 13) | 61 | 67 | |
| 01/26/2022 | L | 253 | Albany (13 - 18) | 62 | 64 | ||
| 02/02/2022 | W | at | 352 | Maine (6 - 23) | 62 | 50 | |
| 02/05/2022 | L | 29 | Vermont (28 - 5) | 67 | 78 | ||
| 02/07/2022 | W | 269 | Hartford (12 - 20) | 85 | 75 | ||
| 02/09/2022 | L | at | 155 | Stony Brook (18 - 13) | 85 | 87 | |
| 02/12/2022 | W | 176 | UMBC (18 - 14) | 88 | 71 | ||
| 02/16/2022 | L | at | 283 | NJIT (11 - 18) | 55 | 59 | |
| 02/19/2022 | L | 267 | Binghamton (12 - 17) | 64 | 78 | ||
| 02/23/2022 | W | 155 | Stony Brook (18 - 13) | 67 | 50 | ||
| 02/26/2022 | L | at | 29 | Vermont (28 - 5) | 61 | 62 | |
| 03/01/2022 | L | 204 | New Hampshire (15 - 13) | 48 | 64 | ||
| 03/03/2022 | W | at | 269 | Hartford (12 - 20) | 83 | 73 | |
| 03/06/2022 | L | at | 176 | UMBC (18 - 14) | 85 | 93 |