| Team: | Cleveland St. | Rating: | 3.7857 | Average Socre: | 75.6 |
| Conference: | Horizon | ||||
| Wins: | 20 | Losses: | 10 | Div 1 Games: | 28 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 54 | BYU (22 - 10) | 59 | 69 | |
| 11/13/2021 | L | 65 | Ohio (24 - 9) | 56 | 67 | ||
| 11/16/2021 | W | Edinboro ( - ) | 75 | 61 | |||
| 11/20/2021 | W | 270 | Canisius (11 - 21) | 80 | 70 | ||
| 11/22/2021 | W | 296 | Coppin St. (9 - 23) | 65 | 62 | ||
| 11/27/2021 | W | Penn State Behrend ( - ) | 89 | 47 | |||
| 12/02/2021 | W | 148 | Northern Kentucky (20 - 12) | 72 | 58 | ||
| 12/04/2021 | W | 139 | Wright St. (21 - 13) | 85 | 75 | ||
| 12/13/2021 | L | at | 126 | Oklahoma St. (15 - 15) | 93 | 98 | |
| 12/30/2021 | W | 129 | Purdue Fort Wayne (21 - 11) | 90 | 81 | ||
| 01/05/2022 | W | 129 | Purdue Fort Wayne (21 - 11) | 65 | 58 | ||
| 01/07/2022 | W | at | 329 | Robert Morris (8 - 24) | 78 | 77 | |
| 01/09/2022 | W | at | 214 | Youngstown St. (18 - 14) | 86 | 80 | |
| 01/13/2022 | L | 125 | Oakland (20 - 12) | 65 | 70 | ||
| 01/15/2022 | W | 215 | Detroit Mercy (14 - 15) | 72 | 70 | ||
| 01/21/2022 | W | 214 | Youngstown St. (18 - 14) | 64 | 61 | ||
| 01/23/2022 | W | 329 | Robert Morris (8 - 24) | 75 | 68 | ||
| 01/28/2022 | W | at | 139 | Wright St. (21 - 13) | 71 | 67 | |
| 01/30/2022 | L | at | 148 | Northern Kentucky (20 - 12) | 72 | 78 | |
| 02/04/2022 | W | 351 | Green Bay (5 - 25) | 85 | 69 | ||
| 02/06/2022 | W | 311 | Milwaukee (10 - 22) | 84 | 71 | ||
| 02/10/2022 | L | 247 | Illinois Chicago (14 - 16) | 75 | 76 | ||
| 02/12/2022 | W | 358 | IUPUI (3 - 26) | 83 | 45 | ||
| 02/14/2022 | L | at | 129 | Purdue Fort Wayne (21 - 11) | 98 | 102 | |
| 02/18/2022 | W | at | 311 | Milwaukee (10 - 22) | 78 | 61 | |
| 02/20/2022 | W | at | 351 | Green Bay (5 - 25) | 79 | 67 | |
| 02/24/2022 | L | at | 215 | Detroit Mercy (14 - 15) | 67 | 74 | |
| 02/26/2022 | L | at | 125 | Oakland (20 - 12) | 57 | 65 | |
| 03/03/2022 | W | 329 | Robert Morris (8 - 24) | 83 | 67 | ||
| 03/07/2022 | L | 139 | Wright St. (21 - 13) | 67 | 82 | Indianapolis, IN |