| Team: | Mississippi St. | Rating: | 3.8485 | Average Socre: | 70.8788 |
| Conference: | SEC | ||||
| Wins: | 18 | Losses: | 15 | Div 1 Games: | 33 |
| Date | Rnk | Team | Location | ||||
| 11/10/2021 | W | 338 | North Alabama (9 - 21) | 75 | 49 | ||
| 11/13/2021 | W | 202 | Montana (18 - 14) | 86 | 49 | ||
| 11/17/2021 | W | 215 | Detroit Mercy (14 - 15) | 77 | 64 | ||
| 11/21/2021 | W | 96 | Morehead St. (23 - 11) | 66 | 46 | ||
| 11/25/2021 | L | 210 | Louisville (13 - 19) | 58 | 72 | Nassau, Bahamas | |
| 11/27/2021 | W | 58 | Richmond (23 - 12) | 82 | 71 | Nassau, Bahamas | |
| 12/02/2021 | W | 357 | Lamar (2 - 27) | 75 | 60 | ||
| 12/05/2021 | L | 179 | Minnesota (13 - 17) | 76 | 81 | ||
| 12/11/2021 | L | 9 | Colorado St. (25 - 5) | 63 | 66 | Fort Worth, TX | |
| 12/14/2021 | W | 132 | Georgia St. (18 - 10) | 79 | 50 | ||
| 12/17/2021 | W | 77 | Furman (22 - 12) | 69 | 66 | ||
| 12/21/2021 | W | 84 | Winthrop (23 - 9) | 84 | 63 | Jackson, MS | |
| 12/29/2021 | W | 27 | Arkansas (25 - 8) | 81 | 68 | ||
| 01/08/2022 | L | at | 209 | Mississippi (13 - 19) | 72 | 82 | |
| 01/12/2022 | W | 320 | Georgia (6 - 26) | 88 | 72 | ||
| 01/15/2022 | W | 43 | Alabama (19 - 13) | 78 | 76 | ||
| 01/19/2022 | L | at | 106 | Florida (19 - 13) | 72 | 80 | |
| 01/22/2022 | W | 209 | Mississippi (13 - 19) | 78 | 60 | ||
| 01/25/2022 | L | at | 13 | Kentucky (26 - 7) | 74 | 82 | |
| 01/29/2022 | L | at | 31 | Texas Tech (25 - 9) | 50 | 76 | |
| 02/01/2022 | W | 97 | South Carolina (18 - 13) | 78 | 64 | ||
| 02/05/2022 | L | at | 27 | Arkansas (25 - 8) | 55 | 63 | |
| 02/09/2022 | L | 6 | Tennessee (26 - 7) | 63 | 72 | ||
| 02/12/2022 | L | at | 39 | LSU (22 - 11) | 65 | 69 | |
| 02/16/2022 | L | at | 43 | Alabama (19 - 13) | 75 | 80 | |
| 02/18/2022 | W | 238 | Missouri (12 - 21) | 68 | 49 | ||
| 02/20/2022 | W | at | 238 | Missouri (12 - 21) | 58 | 56 | |
| 02/23/2022 | L | at | 97 | South Carolina (18 - 13) | 56 | 66 | |
| 02/26/2022 | W | 134 | Vanderbilt (17 - 16) | 74 | 69 | ||
| 03/02/2022 | L | 5 | Auburn (27 - 5) | 68 | 81 | ||
| 03/05/2022 | L | at | 63 | Texas A&M (23 - 12) | 64 | 67 | |
| 03/10/2022 | W | at | 97 | South Carolina (18 - 13) | 73 | 51 | Tampa, FL |
| 03/11/2022 | L | at | 6 | Tennessee (26 - 7) | 59 | 72 | Tampa, FL |