| Team: | Purdue Fort Wayne | Rating: | 3.0667 | Average Socre: | 73.7188 |
| Conference: | Horizon | ||||
| Wins: | 21 | Losses: | 11 | Div 1 Games: | 30 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | Earlham ( - ) | 103 | 54 | |||
| 11/16/2021 | W | 275 | Austin Peay (12 - 17) | 65 | 60 | ||
| 11/19/2021 | L | at | 179 | Minnesota (13 - 17) | 49 | 78 | |
| 11/26/2021 | W | 174 | Southeastern Louisiana (19 - 14) | 74 | 66 | Fort Myers, FL | |
| 11/27/2021 | L | at | 316 | Western Michigan (8 - 23) | 85 | 93 | Fort Myers, FL |
| 11/28/2021 | L | at | 115 | Florida Gulf Coast (21 - 11) | 78 | 85 | |
| 12/02/2021 | L | 139 | Wright St. (21 - 13) | 73 | 86 | ||
| 12/04/2021 | W | 148 | Northern Kentucky (20 - 12) | 71 | 57 | ||
| 12/08/2021 | L | at | 302 | SIU Edwardsville (11 - 21) | 59 | 80 | |
| 12/11/2021 | W | 234 | Southeast Missouri St. (14 - 18) | 78 | 65 | ||
| 12/30/2021 | L | at | 111 | Cleveland St. (20 - 10) | 81 | 90 | |
| 01/05/2022 | L | at | 111 | Cleveland St. (20 - 10) | 58 | 65 | |
| 01/07/2022 | W | at | 214 | Youngstown St. (18 - 14) | 71 | 61 | |
| 01/09/2022 | W | at | 329 | Robert Morris (8 - 24) | 76 | 70 | |
| 01/13/2022 | W | 215 | Detroit Mercy (14 - 15) | 62 | 60 | ||
| 01/15/2022 | L | 125 | Oakland (20 - 12) | 68 | 76 | ||
| 01/17/2022 | W | Michigan Dearborn ( - ) | 102 | 59 | |||
| 01/21/2022 | W | 329 | Robert Morris (8 - 24) | 86 | 62 | ||
| 01/23/2022 | W | 214 | Youngstown St. (18 - 14) | 82 | 71 | ||
| 01/28/2022 | L | at | 148 | Northern Kentucky (20 - 12) | 49 | 59 | |
| 01/30/2022 | L | at | 139 | Wright St. (21 - 13) | 63 | 75 | |
| 02/04/2022 | W | 311 | Milwaukee (10 - 22) | 70 | 60 | ||
| 02/06/2022 | W | 351 | Green Bay (5 - 25) | 71 | 55 | ||
| 02/10/2022 | W | 358 | IUPUI (3 - 26) | 72 | 57 | ||
| 02/12/2022 | W | 247 | Illinois Chicago (14 - 16) | 73 | 66 | ||
| 02/14/2022 | W | 111 | Cleveland St. (20 - 10) | 102 | 98 | ||
| 02/18/2022 | W | at | 351 | Green Bay (5 - 25) | 74 | 55 | |
| 02/20/2022 | W | at | 311 | Milwaukee (10 - 22) | 81 | 71 | |
| 02/24/2022 | W | at | 125 | Oakland (20 - 12) | 81 | 70 | |
| 02/26/2022 | W | at | 215 | Detroit Mercy (14 - 15) | 81 | 78 | |
| 03/03/2022 | W | 247 | Illinois Chicago (14 - 16) | 78 | 72 | ||
| 03/07/2022 | L | 148 | Northern Kentucky (20 - 12) | 43 | 57 | Indianapolis, IN |