| Team: | IUPUI | Rating: | -15.9259 | Average Socre: | 52.4483 |
| Conference: | Horizon | ||||
| Wins: | 3 | Losses: | 26 | Div 1 Games: | 27 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 205 | Butler (14 - 19) | 47 | 56 | |
| 11/11/2021 | L | at | 342 | Evansville (6 - 24) | 40 | 60 | |
| 11/15/2021 | L | 284 | Denver (11 - 21) | 47 | 63 | San Antonio, TX | |
| 11/16/2021 | L | 167 | Texas A&M Corpus Chris (23 - 11) | 59 | 65 | San Antonio, TX | |
| 11/17/2021 | L | at | 323 | UTSA (10 - 22) | 57 | 60 | |
| 11/23/2021 | W | Spalding ( - ) | 61 | 41 | |||
| 12/02/2021 | L | 215 | Detroit Mercy (14 - 15) | 45 | 69 | ||
| 12/04/2021 | L | 125 | Oakland (20 - 12) | 45 | 78 | ||
| 12/10/2021 | L | at | 277 | Tennessee St. (14 - 18) | 44 | 70 | |
| 12/16/2021 | L | 327 | Chicago St. (7 - 25) | 55 | 61 | ||
| 12/21/2021 | L | 96 | Morehead St. (23 - 11) | 52 | 80 | ||
| 01/08/2022 | L | at | 139 | Wright St. (21 - 13) | 58 | 72 | |
| 01/10/2022 | L | 247 | Illinois Chicago (14 - 16) | 65 | 67 | ||
| 01/13/2022 | L | at | 351 | Green Bay (5 - 25) | 54 | 69 | |
| 01/15/2022 | L | at | 311 | Milwaukee (10 - 22) | 54 | 89 | |
| 01/18/2022 | L | at | 76 | Ohio St. (19 - 11) | 37 | 83 | |
| 01/20/2022 | L | 139 | Wright St. (21 - 13) | 45 | 73 | ||
| 01/22/2022 | L | 148 | Northern Kentucky (20 - 12) | 41 | 60 | ||
| 01/31/2022 | W | East West ( - ) | 75 | 59 | |||
| 02/03/2022 | L | 214 | Youngstown St. (18 - 14) | 55 | 61 | ||
| 02/05/2022 | L | 329 | Robert Morris (8 - 24) | 49 | 66 | ||
| 02/10/2022 | L | at | 129 | Purdue Fort Wayne (21 - 11) | 57 | 72 | |
| 02/12/2022 | L | at | 111 | Cleveland St. (20 - 10) | 45 | 83 | |
| 02/14/2022 | L | at | 247 | Illinois Chicago (14 - 16) | 54 | 57 | |
| 02/17/2022 | W | at | 329 | Robert Morris (8 - 24) | 66 | 56 | |
| 02/19/2022 | L | at | 214 | Youngstown St. (18 - 14) | 61 | 74 | |
| 02/24/2022 | L | 311 | Milwaukee (10 - 22) | 54 | 66 | ||
| 02/26/2022 | L | 351 | Green Bay (5 - 25) | 41 | 67 | ||
| 03/01/2022 | L | at | 125 | Oakland (20 - 12) | 58 | 69 |