| Team: | Hofstra | Rating: | 4.9667 | Average Socre: | 77.9375 |
| Conference: | Colonial | ||||
| Wins: | 21 | Losses: | 11 | Div 1 Games: | 30 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 7 | Houston (29 - 5) | 75 | 83 | |
| 11/13/2021 | W | at | 334 | Duquesne (6 - 24) | 73 | 63 | |
| 11/16/2021 | L | at | 25 | Iona (25 - 7) | 74 | 82 | |
| 11/19/2021 | L | at | 163 | Maryland (15 - 17) | 67 | 69 | |
| 11/22/2021 | L | at | 58 | Richmond (23 - 12) | 68 | 81 | |
| 11/24/2021 | W | Molloy ( - ) | 87 | 49 | |||
| 11/27/2021 | W | 215 | Detroit Mercy (14 - 15) | 98 | 84 | ||
| 12/01/2021 | W | 71 | Princeton (23 - 6) | 81 | 77 | ||
| 12/04/2021 | W | 324 | Bucknell (9 - 23) | 88 | 69 | ||
| 12/08/2021 | L | at | 155 | Stony Brook (18 - 13) | 62 | 79 | |
| 12/12/2021 | W | John Jay ( - ) | 102 | 51 | |||
| 12/18/2021 | W | at | 27 | Arkansas (25 - 8) | 89 | 81 | North Little Rock, AR |
| 12/22/2021 | W | at | 94 | Monmouth (21 - 13) | 77 | 71 | |
| 12/29/2021 | L | at | 346 | William & Mary (5 - 27) | 62 | 63 | |
| 01/09/2022 | W | at | 182 | James Madison (15 - 14) | 87 | 80 | |
| 01/11/2022 | L | at | 47 | Towson (25 - 8) | 66 | 78 | |
| 01/15/2022 | W | 91 | Delaware (22 - 12) | 82 | 77 | ||
| 01/17/2022 | W | 185 | Drexel (15 - 14) | 71 | 68 | ||
| 01/22/2022 | W | at | 281 | Northeastern (9 - 22) | 72 | 50 | |
| 01/27/2022 | W | at | 160 | Charleston (17 - 15) | 76 | 73 | |
| 01/29/2022 | L | at | 85 | UNC Wilmington (23 - 9) | 72 | 78 | |
| 02/03/2022 | L | 47 | Towson (25 - 8) | 68 | 78 | ||
| 02/05/2022 | W | 182 | James Madison (15 - 14) | 85 | 78 | ||
| 02/07/2022 | W | 85 | UNC Wilmington (23 - 9) | 73 | 71 | ||
| 02/10/2022 | W | at | 185 | Drexel (15 - 14) | 83 | 73 | |
| 02/12/2022 | W | at | 91 | Delaware (22 - 12) | 80 | 66 | |
| 02/15/2022 | W | at | 286 | Elon (10 - 22) | 97 | 64 | |
| 02/19/2022 | W | 281 | Northeastern (9 - 22) | 76 | 73 | ||
| 02/24/2022 | L | 286 | Elon (10 - 22) | 55 | 81 | ||
| 02/26/2022 | W | 346 | William & Mary (5 - 27) | 83 | 67 | ||
| 02/28/2022 | W | 160 | Charleston (17 - 15) | 89 | 84 | ||
| 03/06/2022 | L | 160 | Charleston (17 - 15) | 76 | 92 | Washington, DC |