| Team: | UC Irvine | Rating: | 2.5652 | Average Socre: | 66.24 |
| Conference: | Big West | ||||
| Wins: | 15 | Losses: | 10 | Div 1 Games: | 23 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 21 | New Mexico St. (26 - 6) | 51 | 62 | |
| 11/13/2021 | W | 20 | Boise St. (27 - 7) | 58 | 50 | ||
| 11/16/2021 | W | La Verne ( - ) | 100 | 41 | |||
| 11/20/2021 | W | 325 | Pepperdine (7 - 25) | 82 | 48 | ||
| 11/27/2021 | W | at | 64 | Santa Clara (21 - 11) | 69 | 64 | |
| 12/03/2021 | W | Bethesda ( - ) | 86 | 54 | |||
| 12/11/2021 | L | at | 135 | Fresno St. (19 - 13) | 55 | 63 | |
| 12/15/2021 | L | at | 32 | USC (26 - 7) | 61 | 66 | |
| 12/19/2021 | L | at | 334 | Duquesne (6 - 24) | 54 | 76 | Akron, OH |
| 01/08/2022 | W | at | 162 | UC Riverside (16 - 12) | 68 | 51 | |
| 01/13/2022 | L | at | 165 | Hawaii (17 - 11) | 56 | 72 | |
| 01/20/2022 | L | 119 | Cal St. Fullerton (21 - 10) | 63 | 65 | ||
| 01/22/2022 | L | at | 104 | Long Beach St. (20 - 12) | 67 | 73 | |
| 01/27/2022 | W | 308 | Cal St. Bakersfield (8 - 19) | 57 | 52 | ||
| 01/29/2022 | W | 331 | Cal Poly (7 - 21) | 72 | 48 | ||
| 02/03/2022 | W | at | 171 | UC Santa Barbara (17 - 11) | 53 | 52 | |
| 02/05/2022 | W | at | 309 | Cal St. Northridge (7 - 23) | 75 | 70 | |
| 02/10/2022 | W | 162 | UC Riverside (16 - 12) | 66 | 56 | ||
| 02/15/2022 | W | at | 255 | UC San Diego (13 - 16) | 56 | 50 | |
| 02/19/2022 | W | 165 | Hawaii (17 - 11) | 77 | 52 | ||
| 02/24/2022 | L | at | 119 | Cal St. Fullerton (21 - 10) | 64 | 66 | |
| 02/26/2022 | W | 104 | Long Beach St. (20 - 12) | 77 | 72 | ||
| 03/03/2022 | L | at | 331 | Cal Poly (7 - 21) | 54 | 65 | |
| 03/05/2022 | W | at | 308 | Cal St. Bakersfield (8 - 19) | 66 | 61 | |
| 03/10/2022 | L | 171 | UC Santa Barbara (17 - 11) | 69 | 78 | Henderson, NV |