| Team: | UC San Diego | Rating: | -3.3704 | Average Socre: | 70.2069 |
| Conference: | Big West | ||||
| Wins: | 13 | Losses: | 16 | Div 1 Games: | 27 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | at | 237 | California (12 - 20) | 80 | 67 | |
| 11/13/2021 | W | 236 | George Washington (12 - 18) | 75 | 55 | ||
| 11/16/2021 | W | San Diego Christian ( - ) | 97 | 60 | |||
| 11/20/2021 | W | at | 288 | Sacramento St. (11 - 18) | 71 | 56 | |
| 11/24/2021 | L | at | 202 | Montana (18 - 14) | 61 | 71 | |
| 11/25/2021 | L | at | 340 | Southern Miss (7 - 26) | 55 | 56 | Missoula, MT |
| 12/02/2021 | W | 300 | Eastern Michigan (10 - 21) | 83 | 74 | ||
| 12/12/2021 | L | at | 80 | Seattle (23 - 9) | 51 | 73 | |
| 12/15/2021 | L | at | 284 | Denver (11 - 21) | 56 | 64 | |
| 12/18/2021 | W | Cal Tech ( - ) | 93 | 52 | |||
| 12/22/2021 | L | at | 26 | San Diego St. (23 - 8) | 57 | 78 | |
| 12/30/2021 | W | 171 | UC Santa Barbara (17 - 11) | 85 | 83 | ||
| 01/01/2022 | W | 309 | Cal St. Northridge (7 - 23) | 72 | 64 | ||
| 01/06/2022 | L | at | 162 | UC Riverside (16 - 12) | 51 | 59 | |
| 01/08/2022 | L | at | 200 | UC Davis (13 - 11) | 71 | 78 | |
| 01/15/2022 | L | at | 165 | Hawaii (17 - 11) | 56 | 79 | |
| 01/20/2022 | L | 104 | Long Beach St. (20 - 12) | 69 | 87 | ||
| 01/22/2022 | L | at | 119 | Cal St. Fullerton (21 - 10) | 80 | 83 | |
| 01/27/2022 | L | 331 | Cal Poly (7 - 21) | 55 | 59 | ||
| 01/29/2022 | W | 308 | Cal St. Bakersfield (8 - 19) | 83 | 75 | ||
| 02/03/2022 | W | at | 309 | Cal St. Northridge (7 - 23) | 83 | 77 | |
| 02/05/2022 | L | at | 171 | UC Santa Barbara (17 - 11) | 48 | 84 | |
| 02/12/2022 | W | 162 | UC Riverside (16 - 12) | 85 | 62 | ||
| 02/15/2022 | L | 146 | UC Irvine (15 - 10) | 50 | 56 | ||
| 02/17/2022 | L | 165 | Hawaii (17 - 11) | 53 | 65 | ||
| 02/24/2022 | L | at | 104 | Long Beach St. (20 - 12) | 87 | 103 | |
| 02/26/2022 | W | 119 | Cal St. Fullerton (21 - 10) | 81 | 76 | ||
| 03/03/2022 | W | at | 308 | Cal St. Bakersfield (8 - 19) | 72 | 70 | |
| 03/05/2022 | L | at | 331 | Cal Poly (7 - 21) | 76 | 80 |