| Team: | Nicholls St. | Rating: | 2.2143 | Average Socre: | 79.125 |
| Conference: | Southland | ||||
| Wins: | 21 | Losses: | 11 | Div 1 Games: | 28 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | at | 82 | Northern Iowa (19 - 11) | 62 | 58 | |
| 11/12/2021 | W | Carver ( - ) | 120 | 52 | |||
| 11/13/2021 | W | Carver ( - ) | 101 | 44 | |||
| 11/15/2021 | L | at | 12 | Baylor (26 - 6) | 60 | 89 | |
| 11/18/2021 | L | at | 72 | TCU (20 - 12) | 50 | 63 | |
| 11/22/2021 | W | 331 | Cal Poly (7 - 21) | 75 | 72 | San Juan Capistrano, CA | |
| 11/24/2021 | L | at | 93 | Utah Valley (20 - 12) | 63 | 74 | San Juan Capistrano, CA |
| 11/27/2021 | W | Southwestern Christian ( - ) | 87 | 58 | |||
| 12/09/2021 | W | at | 356 | Mississippi Valley St. (2 - 26) | 95 | 80 | |
| 12/13/2021 | W | Blue Mountain ( - ) | 87 | 69 | |||
| 12/15/2021 | L | at | 18 | Wisconsin (24 - 7) | 68 | 71 | |
| 12/18/2021 | W | 356 | Mississippi Valley St. (2 - 26) | 104 | 73 | ||
| 12/21/2021 | L | at | 344 | Oregon St. (3 - 28) | 61 | 83 | |
| 12/29/2021 | L | at | 15 | Purdue (27 - 7) | 90 | 104 | |
| 01/06/2022 | W | at | 339 | Incarnate Word (7 - 25) | 87 | 56 | Katy, TX |
| 01/07/2022 | W | 167 | Texas A&M Corpus Chris (23 - 11) | 84 | 75 | Katy, TX | |
| 01/08/2022 | L | 174 | Southeastern Louisiana (19 - 14) | 72 | 77 | Katy, TX | |
| 01/15/2022 | L | at | 201 | New Orleans (18 - 13) | 66 | 78 | |
| 01/20/2022 | W | 335 | Northwestern St. (9 - 23) | 69 | 58 | ||
| 01/22/2022 | L | 174 | Southeastern Louisiana (19 - 14) | 93 | 101 | ||
| 01/27/2022 | W | at | 314 | McNeese St. (11 - 22) | 81 | 71 | |
| 01/29/2022 | W | at | 317 | Houston Baptist (11 - 18) | 73 | 61 | |
| 02/03/2022 | W | at | 339 | Incarnate Word (7 - 25) | 63 | 60 | |
| 02/10/2022 | W | 339 | Incarnate Word (7 - 25) | 69 | 58 | ||
| 02/12/2022 | W | 167 | Texas A&M Corpus Chris (23 - 11) | 83 | 80 | ||
| 02/17/2022 | W | 314 | McNeese St. (11 - 22) | 82 | 73 | ||
| 02/19/2022 | W | 317 | Houston Baptist (11 - 18) | 84 | 70 | ||
| 02/24/2022 | W | at | 335 | Northwestern St. (9 - 23) | 80 | 62 | |
| 02/26/2022 | L | at | 174 | Southeastern Louisiana (19 - 14) | 81 | 83 | |
| 03/02/2022 | W | at | 167 | Texas A&M Corpus Chris (23 - 11) | 86 | 75 | |
| 03/05/2022 | W | 201 | New Orleans (18 - 13) | 92 | 85 | ||
| 03/11/2022 | L | 167 | Texas A&M Corpus Chris (23 - 11) | 64 | 71 | Katy, TX |