| Team: | McNeese St. | Rating: | -7.2414 | Average Socre: | 78.1515 |
| Conference: | Southland | ||||
| Wins: | 11 | Losses: | 22 | Div 1 Games: | 29 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 44 | SMU (23 - 8) | 62 | 86 | |
| 11/11/2021 | L | at | 72 | TCU (20 - 12) | 61 | 77 | |
| 11/15/2021 | W | Champion Christian ( - ) | 116 | 66 | |||
| 11/18/2021 | L | at | 39 | LSU (22 - 11) | 46 | 85 | |
| 11/22/2021 | W | Carver ( - ) | 98 | 54 | |||
| 11/26/2021 | W | at | 326 | St. Francis NY (10 - 20) | 71 | 59 | Niceville, FL |
| 11/27/2021 | L | at | 105 | Samford (21 - 11) | 75 | 83 | Niceville, FL |
| 12/01/2021 | L | at | 80 | Seattle (23 - 9) | 62 | 78 | |
| 12/04/2021 | L | at | 36 | Wyoming (25 - 8) | 58 | 79 | |
| 12/08/2021 | L | at | 173 | Louisiana (16 - 15) | 68 | 83 | |
| 12/16/2021 | L | at | 116 | UTEP (19 - 13) | 72 | 82 | |
| 12/21/2021 | L | at | 192 | Kansas St. (14 - 17) | 59 | 74 | |
| 12/30/2021 | W | Ecclesia ( - ) | 115 | 66 | |||
| 01/06/2022 | W | 201 | New Orleans (18 - 13) | 92 | 82 | Katy, TX | |
| 01/07/2022 | L | 174 | Southeastern Louisiana (19 - 14) | 78 | 83 | Katy, TX | |
| 01/08/2022 | L | at | 167 | Texas A&M Corpus Chris (23 - 11) | 54 | 67 | Katy, TX |
| 01/12/2022 | W | Arlington Baptist ( - ) | 120 | 44 | |||
| 01/15/2022 | W | 317 | Houston Baptist (11 - 18) | 78 | 75 | ||
| 01/20/2022 | L | at | 167 | Texas A&M Corpus Chris (23 - 11) | 56 | 60 | |
| 01/22/2022 | W | at | 339 | Incarnate Word (7 - 25) | 82 | 72 | |
| 01/27/2022 | L | 152 | Nicholls St. (21 - 11) | 71 | 81 | ||
| 01/30/2022 | L | 201 | New Orleans (18 - 13) | 78 | 84 | ||
| 02/03/2022 | L | 174 | Southeastern Louisiana (19 - 14) | 78 | 83 | ||
| 02/05/2022 | W | 335 | Northwestern St. (9 - 23) | 93 | 84 | ||
| 02/10/2022 | L | at | 174 | Southeastern Louisiana (19 - 14) | 86 | 91 | |
| 02/12/2022 | W | at | 335 | Northwestern St. (9 - 23) | 80 | 75 | |
| 02/17/2022 | L | at | 152 | Nicholls St. (21 - 11) | 73 | 82 | |
| 02/19/2022 | L | at | 201 | New Orleans (18 - 13) | 75 | 88 | |
| 02/24/2022 | L | 167 | Texas A&M Corpus Chris (23 - 11) | 53 | 65 | ||
| 02/26/2022 | L | 339 | Incarnate Word (7 - 25) | 67 | 69 | ||
| 03/05/2022 | L | at | 317 | Houston Baptist (11 - 18) | 144 | 149 | |
| 03/09/2022 | W | at | 335 | Northwestern St. (9 - 23) | 80 | 67 | Katy, TX |
| 03/10/2022 | L | at | 201 | New Orleans (18 - 13) | 78 | 82 | Katy, TX |