| Team: | Mercer | Rating: | 0.129 | Average Socre: | 70.4545 |
| Conference: | Southern | ||||
| Wins: | 16 | Losses: | 17 | Div 1 Games: | 31 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | L | at | 27 | Arkansas (25 - 8) | 61 | 74 | |
| 11/13/2021 | L | at | 84 | Winthrop (23 - 9) | 85 | 88 | |
| 11/16/2021 | W | Life ( - ) | 78 | 50 | |||
| 11/20/2021 | L | at | 50 | Saint Louis (23 - 11) | 58 | 75 | |
| 11/23/2021 | W | 324 | Bucknell (9 - 23) | 78 | 68 | Riviera Maya, Mexico | |
| 11/24/2021 | L | 62 | Middle Tennessee (23 - 10) | 58 | 82 | Riviera Maya, Mexico | |
| 11/27/2021 | W | Milligan ( - ) | 88 | 49 | |||
| 12/01/2021 | W | at | 274 | Kennesaw St. (13 - 18) | 73 | 71 | |
| 12/04/2021 | W | 132 | Georgia St. (18 - 10) | 83 | 77 | ||
| 12/06/2021 | W | at | 166 | Coastal Carolina (16 - 13) | 74 | 69 | |
| 12/11/2021 | W | 248 | Georgia Southern (13 - 16) | 77 | 68 | ||
| 12/19/2021 | L | at | 115 | Florida Gulf Coast (21 - 11) | 55 | 67 | |
| 12/22/2021 | L | 120 | Troy (20 - 11) | 65 | 69 | ||
| 01/05/2022 | W | 105 | Samford (21 - 11) | 83 | 80 | ||
| 01/08/2022 | L | at | 77 | Furman (22 - 12) | 66 | 81 | |
| 01/13/2022 | W | 181 | VMI (16 - 15) | 97 | 91 | ||
| 01/15/2022 | W | 149 | UNC Greensboro (17 - 14) | 58 | 49 | ||
| 01/17/2022 | W | at | 244 | The Citadel (13 - 18) | 71 | 64 | |
| 01/19/2022 | L | at | 184 | East Tennessee St. (15 - 17) | 64 | 72 | |
| 01/22/2022 | W | 273 | Western Carolina (11 - 21) | 72 | 64 | ||
| 01/26/2022 | L | at | 105 | Samford (21 - 11) | 61 | 75 | |
| 01/29/2022 | L | 77 | Furman (22 - 12) | 50 | 80 | ||
| 01/31/2022 | W | 142 | Wofford (19 - 13) | 67 | 62 | ||
| 02/05/2022 | L | at | 22 | Chattanooga (27 - 7) | 68 | 77 | |
| 02/07/2022 | L | 22 | Chattanooga (27 - 7) | 72 | 74 | ||
| 02/10/2022 | L | at | 181 | VMI (16 - 15) | 79 | 85 | |
| 02/13/2022 | W | at | 149 | UNC Greensboro (17 - 14) | 73 | 64 | |
| 02/16/2022 | W | 184 | East Tennessee St. (15 - 17) | 65 | 56 | ||
| 02/19/2022 | L | at | 273 | Western Carolina (11 - 21) | 65 | 69 | |
| 02/23/2022 | L | 244 | The Citadel (13 - 18) | 67 | 71 | ||
| 02/26/2022 | L | at | 142 | Wofford (19 - 13) | 67 | 74 | |
| 03/04/2022 | W | 273 | Western Carolina (11 - 21) | 81 | 53 | Asheville, NC | |
| 03/05/2022 | L | at | 77 | Furman (22 - 12) | 66 | 80 | Asheville, NC |