| Team: | South Alabama | Rating: | 2.5769 | Average Socre: | 71.3667 |
| Conference: | Sun Belt | ||||
| Wins: | 19 | Losses: | 11 | Div 1 Games: | 26 |
| Date | Rnk | Team | Location | ||||
| 11/09/2021 | W | Spring Hill ( - ) | 102 | 41 | |||
| 11/13/2021 | L | at | 128 | Wichita St. (15 - 13) | 58 | 64 | |
| 11/16/2021 | L | at | 43 | Alabama (19 - 13) | 68 | 73 | |
| 11/20/2021 | W | Mobile ( - ) | 78 | 45 | |||
| 11/22/2021 | W | William Carey ( - ) | 96 | 53 | |||
| 11/25/2021 | W | 219 | San Diego (15 - 16) | 68 | 67 | Paradise, NV | |
| 11/26/2021 | W | at | 165 | Hawaii (17 - 11) | 72 | 69 | Paradise, NV |
| 11/29/2021 | W | Texas A&M Commerce ( - ) | 69 | 66 | |||
| 12/01/2021 | W | 340 | Southern Miss (7 - 26) | 85 | 55 | ||
| 12/04/2021 | W | at | 98 | Jacksonville St. (21 - 10) | 74 | 64 | |
| 12/14/2021 | W | 233 | Tarleton St. (14 - 17) | 69 | 62 | ||
| 12/17/2021 | L | at | 233 | Tarleton St. (14 - 17) | 52 | 65 | |
| 12/21/2021 | W | 302 | SIU Edwardsville (11 - 21) | 84 | 69 | ||
| 12/30/2021 | L | at | 257 | UT Arlington (11 - 18) | 87 | 89 | |
| 01/06/2022 | L | 122 | Appalachian St. (19 - 14) | 64 | 72 | ||
| 01/13/2022 | W | 132 | Georgia St. (18 - 10) | 74 | 65 | ||
| 01/15/2022 | W | 248 | Georgia Southern (13 - 16) | 73 | 67 | ||
| 01/20/2022 | W | at | 173 | Louisiana (16 - 15) | 77 | 70 | |
| 01/22/2022 | W | at | 254 | Louisiana Monroe (13 - 18) | 68 | 56 | |
| 01/27/2022 | W | 120 | Troy (20 - 11) | 82 | 63 | ||
| 01/29/2022 | L | at | 120 | Troy (20 - 11) | 68 | 77 | |
| 02/03/2022 | L | at | 248 | Georgia Southern (13 - 16) | 57 | 58 | |
| 02/05/2022 | L | at | 132 | Georgia St. (18 - 10) | 62 | 69 | |
| 02/10/2022 | W | 301 | Little Rock (9 - 19) | 77 | 46 | ||
| 02/12/2022 | W | 141 | Arkansas St. (18 - 11) | 70 | 51 | ||
| 02/17/2022 | W | at | 166 | Coastal Carolina (16 - 13) | 71 | 68 | |
| 02/19/2022 | L | at | 122 | Appalachian St. (19 - 14) | 51 | 69 | |
| 02/23/2022 | L | 69 | Texas St. (21 - 7) | 52 | 55 | ||
| 02/25/2022 | W | 257 | UT Arlington (11 - 18) | 62 | 52 | ||
| 03/03/2022 | L | 301 | Little Rock (9 - 19) | 71 | 75 | Pensacola, FL |